Immune modulatory function of abundant immune-related microRNAs in microvesicles from bovine colostrum
نویسندگان
چکیده
منابع مشابه
Immune-related MicroRNAs are Abundant in Breast Milk Exosomes
Breast milk is a complex liquid rich in immunological components that affect the development of the infant's immune system. Exosomes are membranous vesicles of endocytic origin that are found in various body fluids and that can mediate intercellular communication. MicroRNAs (miRNAs), a well-defined group of non-coding small RNAs, are packaged inside exosomes in human breast milk. Here, we ident...
متن کاملImmune components of bovine colostrum and milk.
Colostrum and milk provide a complete diet for the neonate. In ruminants, colostrum is also the sole source of initial acquired immunity for the offspring. Milk therefore plays an important role in mammalian host defense. In colostrum, the concentration of immunoglobulins is particularly high, with IgG being the major immunoglobulin class present in ruminant milk, in contrast to IgA being the m...
متن کاملThe Immune Proteins of Bovine Colostrum
The important r61e of the colostrum in the transmission of antibodies from mother to offspring, and particularly in the protection of the new-born in ruminants to infectious disease, has been shown by the work of many investigators (1). Howe has demonstrated by salt fractionation studies that the serum of t)he new-born calf taken prior to suckling is deficient in a globulin fraction, and that t...
متن کاملMicroRNAs as Immune Regulators of Inflammation in Children with Epilepsy
Epilepsy is a chronic clinical syndrome of brain function which is caused by abnormal discharge of neurons. MicroRNAs (MiRNAs) are small noncoding RNAs which act post transcriptionally to regulate negatively protein levels. They affect neuroinflammatory signaling, glial and neuronal structure and function, neurogenesis, cell death, and other processes linked to epileptogenesis. The aim of this ...
متن کاملThe role of microRNAs and phytohormones in plant immune system
The plant-pathogen interaction is a multifactor process that may lead to resistance or susceptible responses of plant to pathogens. During the arms race between plant and pathogens, various biochemical, molecular and physiological events are triggered in plant cells such as ROS signaling, hormone activation and gene expression reprogramming. In plants, microRNAs (miRNAs) are key post-transcript...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Protein & Cell
سال: 2013
ISSN: 1674-800X,1674-8018
DOI: 10.1007/s13238-013-2119-9